Chromatin and Epigenetics 1400-235CHiE

1. Introduction. Chromatin- structure and functions. 2,3. Histone modifications. 4. Histone variants. 5. DNA methylation. 6. Overview of methods used in chromatin biology. 7. Linker histones. 8. Nucleosomal and higher-order chromatin organization 9. Chromatin remodeling. 10. Non-coding RNAs. 11. Epigenetic gene silencing and Polycomb proteins. 12. Epigenetic regulation of animal and plant development. 13. Chromatin and cancer.

Main fields of studies for MISMaP

biology
biotechnology

Type of course

elective monographs

Mode

Classroom

Prerequisites (description)

Students should have basic knowledge about genetics and biochemistry. Completion of courses covering genetics, biochemistry, and molecular biology is recommended.

Course coordinators

Rafał Archacki
Marta Koblowska

Learning outcomes

Students will improve their knowledge about chromatin-based mechanisms of gene regulation and epigenetic phenomena.

Assessment criteria

Exam in a written form (test, close-ended questions).

Practical placement

n/a

Bibliography

1. Epigenetics. C. David Allis, Thomas Jenuwein, Danny Reinberg. CSHL Press, 2007
2. Fundamental Molecular Biology. Lizabeth A. Allison. Wiley, 2011.
3. Recent articles from scientific journals provided by lecturers.

Additional information

Information on level of this course, year of study and semester when the course unit is delivered, types and amount of class hours - can be found in course structure diagrams of apropriate study programmes. This course is related to the following study programmes:

Master's degree, second cycle programme, Bioinformatics and Systems Biology

Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system:

Description of 1400-235CHiE in USOSweb