Radiochemistry 1100-3BF15
1. History and evolution of isotopic methods. Production of radioisotopes.
2. γ emitters. Single photon emission computed tomography (SPECT). Characteristics of the method. Applications. Review and application of basic radiopharmaceuticals based on γ emitters. (3h)
3. β emitters. Positron emission tomography (PET). Characteristics of the method. Applications.
4. Radiochemistry C11. Review and application of basic radiopharmaceuticals based on the C11.
5. F18 radiochemistry. Review and application of basic radiopharmaceuticals based on the F18.
6. O15 radiochemistry. Long-lived isotopes.
7. therapeutic radiopharmaceuticals
8. Fundamentals of pharmaceutical technology. Design of radiopharmaceuticals. Preparation of radiopharmaceuticals.
9. Good Manufacturing Practice
10. Quality control of radiopharmaceuticals.
11th Legislation.
Mode
Prerequisites (description)
Course coordinators
Bibliography
Welch M, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, Wiley, 2005
- Planning a Clinical PET Centre, IAEA Human Health Series vol.11, IAEA 2010
- Cyclotron Produced Radionuclides: Guidelines for Setting Up a Facility Details, IAEA Technical Reports Series No. 471, IAEA 2009;
- Strategies for Clinical Implementation and Quality Management of PET Tracers, IAEA 2009;
Additional information
Information on level of this course, year of study and semester when the course unit is delivered, types and amount of class hours - can be found in course structure diagrams of apropriate study programmes. This course is related to the following study programmes:
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