Physics of biological molecules and macromolecules in aqueous media 1100-2BB112
The course consists of lecture and classes and includes the following issues:
- Properties of water
- Basic concepts of molecular solutions
- Biological particles – types and properties
- Thermodynamics of biological systems
- Intra- and intermolecular interactions
- Electrostatic issues in solutions
- Movement of particles in liquids (diffusion, sedimentation, hydration, viscosity)
Estimated time of work:45 h + 45 h)
30 h – preparation to lecture and classes
30 h – preparation to tests
30 h – preparation to the exam
Total: 180 h (6 ECTS)
Mode
Prerequisites (description)
Course coordinators
Learning outcomes
A successful student:
Knowledge:
1. knows the basic concepts and laws of thermodynamics
2. knows the physical nature of intermolecular interactions
3. knows the physical factors affecting the structure and properties of biological macromolecules
4. knows the basic concepts and laws necessary to describe the movement of molecules in liquids
Skills:
1. knows how to use the language of thermodynamics to describe simple processes occurring in biological systems
2. solves simple problems concerning the movement of molecules in liquids
Assessment criteria
Lectures and classes are obligatory; no more than 4 (lectures:2, classes:2) absences are allowed.
Credit rules:
1. Two written tests during the course
2. Written exam
3. To pass the course, it is necessary to obtain 60% of points in total from tests and written exam.
The grade of the course will be based on the results of the midterm tests and written exam.
Practical placement
not applicable
Bibliography
1. Peter Atkins „Chemia fizyczna” PWN 2007
2. Peter Atkins, Julio de Paula „Chemia fizyczna” PWN 2016
3. Maria Kamińska, Andrzej Witowski i Jerzy Ginter „Wstęp do termodynamiki fenomenologicznej” WUW 2005
4. Ken Dill, Sarina Bromberg „Molecular Driving Forces” GS 2011
5. Tom Waigh „Applied Biophysics” Wiley&Sons 2007
6. Igor Serdyuk, Nathan Zaccai, Joseph Zaccai „Methods in molecular biophysics. Structure, dynamics, function” Cambrige University Press 2007
7. J. Newman, Physics of the life sciences, Springer
8. Loren Dean Williams „Molecular Interactions (Noncovalent Interactions) in biochemical systems”, https://ww2.chemistry.gatech.edu/~lw26/structure/ molecular_interactions/mol_int.html
9. Thomas E. Creighton „Proteins. Structures and Molecular Properties” Freeman and Company 1993
Additional information
Information on level of this course, year of study and semester when the course unit is delivered, types and amount of class hours - can be found in course structure diagrams of apropriate study programmes. This course is related to the following study programmes:
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: