Molecular biology with genetics 2 1000-714BM2
DNA as the genetic material, foundations of classical genetics, human genetics, genetic engineering, types of nucleotide sequences, genomics, evolution of nucleotide sequences, chromatin, DNA replication, mutagenesis and DNA repair, transcription, gene regulation, epigenetic mechanisms, RNA splicing and editing, small regulatory RNAs, translation, protein maturation (folding, posttranslational modifications), protein sorting, protein degradation (ubiquitination,, proteasome, autophagy, N-terminal rule).
Human traits: mendelian and multifactorial, genetic diseases: monogenic and complex, chromosomal aberrations, heritability, cancer genetics, archaeogenomics.
Type of course
Course coordinators
Learning outcomes
Knowledge:
- has knowledge concerning the most important processes in plants and animals and their regulation
- observes and understand the diversity of regulatory systems in biology Abilities and social awareness:
- presentation of the flow of genetic information and its regulation, the rules of heredity, and the fundamentals of genetic engineering
Assessment criteria
written final exam
Bibliography
Genomes 4. T. A. Brown. 2018
Fundamental Molecular Biology, 3rd edition, LA Allison
Additional information
Information on level of this course, year of study and semester when the course unit is delivered, types and amount of class hours - can be found in course structure diagrams of apropriate study programmes. This course is related to the following study programmes:
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