Introduction to bioinformatics 1 1000-711BI1
The lecture and the accompanying laboratory provide the basis for the application of computer science and computational science to the analysis of genes, genomes and proteins. The framework program is as follows:
1. Databases for molecular biology and biotechnology, overview, interdependencies, relational databases.
2. Basic operations on one nucleotide sequence.
3. Comparing two sequences.
4. Searching databases of nucleotide and amino acid sequences using sequences as queries.
5. Comparing multiple sequences.
6. Molecular evolution.
7. Analysis of protein families, representations.
8. Profiles, HMM etc… Advanced methods of finding sequence similarity
9. Sequence themes related to function. Protein family motifs, cell compartment segregation signals, gene expression control sequences.
10. Methods of sequencing and assembling genomes.
11. Differentiation of coding and non-coding DNA sequences (ab initio and homology-based methods).
12. Genome annotation.
13. Comparative (whole genomes) and functional genomics.
Type of course
Completion of the course (exercises + lecture) in the form of an exam will be held remotely using the Kampus platform (multiple choice test).
Information on level of this course, year of study and semester when the course unit is delivered, types and amount of class hours - can be found in course structure diagrams of apropriate study programmes. This course is related to the following study programmes:
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: