Selected topics in functional genomics 1000-2M22TFG
The methods covered in this course are relevant for several of the UN sustainability goals where modern molecular biology is part of the solution, including goals pertaining to food- and bioenergy-production.
There will be lectures/group discussions and supervised computer exercises. The lectures will primarily introduce the students to the theory behind the bioinformatics methods while the labs will show the students how the methods can be used in practice.
Topics of consecutive lectures:
- Introduction to functional genomics
- Transcriptomics
- Differential expression
- Clustering
- Machine learning
- Networks
- Metabolomics and proteomics
- Data integration
Type of course
Learning outcomes
KNOWLEDGE: On completion of this course, the students will have general knowledge of the different data types generated within functional genomics ("omics"-data: transcriptomics, proteomics, metabolomics and epigenomics) and will be able to explain the theory behind the most common bioinformatics methods for analyzing such data. These methods include finding differentially expressed genes and gene sets, machine learning, clustering and network analysis, and methods for integrating "omics" data and biological knowledge in e.g. ontologies.
SKILLS: On completion of this course, the students will be able to analyze "omics" data using different methods and will also be able to understand and interpret the results produced by these methods. Given a data set and a biological question, the students should be able to asses which methods and tools to use in order to answer the question.
GENERAL COMPETENCE: The students will be able to perform reproducible analysis of data generated within functional genomics and be equipped to modify relevant methods when new datatypes emerge in the future.
Assessment criteria
To pass the course, you need to get the two reports from week 1 and week 2 approved.
Bibliography
ENCODE project publications:
https://www.encodeproject.org/publications/
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: