Natural Compounds and Their Impact on Drug Design 1200-3MON5L
The lecture topics are the following: a review on main groups of secondary metabolites with distinguished biological activity (glycosides, alkaloids, steroids, terpenes, antibiotics): the most important plant raw materials; modern methods of increasing of selected metabolites content in plant material; alkaloids with strong activity toward nervous system as lead compounds in the search for counterpain drugs; natural substances exhibiting antineoplastic, mutagenic and carcinogenic activity and their influence on advances of chemotherapy; natural anticancer drugs of plant origin; drug acting on the nervous system and their non-medical application.
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Bibliography
1. Zejc Alfred, Gorczyca Maria "Chemia leków", Wydawnictwo Lekarskie PZWL, 2009
2. Silverman Richard "Chemia organiczna w projektowaniu leków", WNT, 2004
3. Patrick G."Chemia leków. Krótkie wykłady.", PWN, 2009
4. A. Kołodziejczyk „Naturalne związki organiczne", PWN, Warszawa 2006
5. E. J. Corey, Barbara Czakó, László Kürti "Molecules and Medicine", J. Wiley & Sons, 2007
Notes
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Term 2023L:
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