Organic Synthesis Laboratory 1200-2EN-ORSLA1M
Depending on the level of the laboratory skills, students are provided with the structure and/or name of the target compound and are obliged to find experimental procedures in the available chemical literature or procedures are provided by a teacher. Using computerized chemical databases e.g. Reaxys strongly encouraged. Proposed syntheses are at least three stage and allows students to learn about relationship between chemical yield of the single stage and final yield of the synthesis. Students improve their skills in work under anhydrous conditions, diminished pressure and separation of compound by column chromatography. Modern spectroscopy methods are used for the elucidation of the structure of synthesized compounds. The selection of the target compound is based on the actual research conducted at the Faculty of Chemistry.
Type of course
Mode
Prerequisites (description)
Course coordinators
Learning outcomes
Student should achieve ability to use special synthetic methods and good knowledge of using modern chemical databases and chemistry journals for planning organic syntheses. Should be able to analyze reaction using TLC and isolate products by "flash" chromatography.
Assessment criteria
Grading on the basis of the work in the laboratory (quality of the work, NOT the chemical yield of the reaction), and description of the synthesis and final test.
Practical placement
Not applicable
Bibliography
1.A. Vogel Vogel's textbook of practical organic chemistry
2. www.reaxys.com
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: