Biochemistry 1200-2BIOCHW1M
Structure of nucleic acids and their properties. Eukaryotic genome organization. Eukaryotic DNA replication, transcription and protein biosynthesis (translation). Protein targeting in Eukaryotes. Gene expression regulation. The primary, secondary, three-dimensional and quaternary structure of proteins. Protein motifs nad domains. The relationship between protein structure and its function (hemoglobin and mioglobin). Collagen: the fibrous proteins of the matrix. Post-translational protein modifications. Biological catalysis. Structure of enzymes and mechanisms of their action. Regulation of enzyme activity. Molecular logic of metabolism. High energy compouds, phosphorylation potencial. The digestive system.Glycolysis and its regulation.Anaerobic metabolism: lactic fermentation.The citric acid cycle and its role and regulation. Electron transport, oxidative phosphorylation and oxygen metabolism. Gluconeogenesis, glycogen metabolism and the pentose phosphate pathway.Amino acid metabolism.
Main fields of studies for MISMaP
Type of course
Mode
Prerequisites (description)
Course coordinators
Learning outcomes
Understand role nad place of chemistry in science and medical science and understand its contribution in the development of our civilazation
Know essential chemical components of living organisms, their structure, chemical properties and the role in biological processes, know and understand the relationship between molecules structure and their function.
Own basic knowledge about physiological processes and operation of main organs and medical consequences of metabolic processes disorders. Know structure of cells and role and operation of essentials cell structures.
Assessment criteria
In accordance The Rules Of Study At The University Of Warsaw, participation in classes is obligatory. Permitted number of absences from a lecture – 3.
Written exam; to pass minimum 60% of points is needed
Practical placement
no interships
Bibliography
J.M. Berg, J.L. Tymoczko, L. Stryer, Biochemistry
H.R. Matthews, R.A. Freedland, R.L. Miesfeld, Biochemistry short course
B. Alberts, D. Bray, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter Essential cell biology
Allison Lizabeth A. Fundamental Molecular Biology
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: