Methods of Organic Compounds Identification B 1200-1MIZOBW6
Introduction to various methods for identification and structure elucidation of organic compounds as well as the assessment of their purity. Topics encompass the fllowing points:
1. Identification of organic compounds by classical methods:
- elemental analysis of organic compounds
- solubility groups
- identification of functional groups
- separation of mixtures of organic compounds
2. Spectroscopic methods:
- infrared spectroscopy (IR)
- ultraviolet and visible spectrum spectroscopy (UV-VIS)
- hydrogen nuclear magnetic resonance spectroscopy (1H NMR)
- hydrogen nuclear magnetic resonance spectroscopy (13 CNMR) and two-dimensional methods
- mass spectrometry (MS)
3. Identification of organic compounds by chromatographic methods:
- chromatographic methods, thin layer chromatography
- column chromatography
- HPLC
- gas chromatography
4. Complementary methods:
- crystallography
- titration
- TGA, DSC, XPS
Type of course
Mode
Prerequisites (description)
Course coordinators
Learning outcomes
After the completion of the course the following tasks should be accomplished:
a) theoretical and applied know-how for structure determination of organic compounds,
b) general knowledge of chromatographic methods for separation and purification of organic compounds based on their physical state,
c) understanding how to determine the types of functional groups by spectroscopic methods,
d) ability to identify simply organic compounds by 1H-, 13C-NMR and Mass Spectrometry (MS).
Assessment criteria
Written exam or passing two colloquia, otherwise a retake exam (during the secoond examination period). Each time it will be a test with a set of open or closed questions. Mark is calculated based on the % of points acquired in respect of the maximal treshold: 5 (90-100%), 4,5 (80-89%), 4 (70-79%), 3,5 (60-69%), 3 (51-59%). Absence is not penalized.
Practical placement
not applicable
Bibliography
1.John Mc Muray, Organic Chemistry, An International Thomson Publishing Company, 1996
2.Robert M. Silverstein , Francis X. Webster, David J. Kiemle, Spectrometric Identification of Organic Compounds, John Wiley and Sons Inc., 2005
3. John C. Gilbert , Stephen F. Martin, Experimental Organic Chemistry: A Miniscale and Microscale Approach (Available Titles CourseMate) 5th Edition, , wyd. Cengage Learning Laboratory Series
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: