Nanomaterials in Medical Chemistry 1200-1CHMNANW6
Historical perspective and introduction to nanomaterials. Importance of nanoscale, definition and classification of nanomaterials in terms of size, shape and composite material. Analytical methods (quantitative and qualitative), physicochemical and structural techniques used in the study of nanostructures. Lipid nanoparticles: Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLC). Polymer nanoparticles, nanogels and dendrimers. Methods of lipid, polymer and dendrimeric nanomaterials synthesis. The importance of microfluidic techniques in nanostructure technology and tissue engineering. Porous and mesoporous silica nanomaterials. Metallic nanoparticles, methods of production, modification and functionalization. Magnetic and superparamagnetic nanoparticles. Carbon nanomaterials. Application of nanomaterials as drug carriers. Nanomaterials in regenerative medicine. Nanosensors in medical diagnostics. Nanomaterials in medical imaging.
Type of course
Course coordinators
Learning outcomes
After completion of the course the student:
- knows the classification of nanostructures in terms of size, shape and composite material;
-knows the general chemical composition, properties and structural elements of lipid and polymer nanostructures, dendrimers, silica-based nanostructures, metallic, magnetic and hybrid nanoparticles;
- knows the methods of synthesis and analytical techniques allowing the determination of physicochemical parameters of nanostructures;
- knows the cellular mechanisms that enable the effective use of nanomaterials in medicine;
- can provide examples of nanomaterials applications in medicine;
- is able to assess the possibility of using individual nanostructures depending on the size, structure and chemical functionalization.
Assessment criteria
Post-course exam (30 test questions)
Practical placement
N/A
Bibliography
1. Principles of Nanomedicine. Bhattacharjee S. Jenny Stanford Publishing, 2019 Singapore.
2. Handbook of nanotechnology. Bharat B. (Ed). Springer-Verlag 2010, Berlin.
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: