Medical Virology 1400-227WL

Characterization of viruses: structure: nucleic acids, proteins, morphological virus types, lipids, replication cycle of human viruses, defective parts. Classification of viruses: DNA viruses, RNA viruses. Pathogenesis of viral infections. Host defense mechanisms working of immune system in virus disease. Diagnostics of virus infections: isolation and identification of viruses, serological and molecular diagnostics of virus infections. Antiviral therapy. Detailed characterization of virus families that cause human viral diseases. Characterization of following virus families: (1) Herpesviridae; (2) Adenoviridae; (3) Papillomaviridae; (4) Polyomaviridae; (5) Poxviridae; (6) Anelloviridae; (7) Mycodnaviridae; (8) Parvoviridae; (9) Reoviridae; (10) Coronaviridae; (11) Astroviridae; (12) Caliciviridae; (13) Flaviviridae; (14) Picornaviridae; (15) Togaviridae; (16) Rhabdoviridae; (17) Filoviridae; (18); (19) Pneumoviridae; (20) Arenaviridae; (21) Peribunyaviridae; (22) Hantaviridae; (23) Nairoviridae; (24) Pheniuviridae; (25) Orthomyxoviridae; (26) rodzaj Deltavirus; (27) Retroviridae; (28) Hepadnaviridae.

Type of course

obligatory courses

Mode

Classroom

Prerequisites (description)

(in Polish) Obowiązkowy dla kierunku biotechnologia, specjalność biotechnologia medyczna oraz fakultatywny dla studentów III roku studiów licencjackich oraz I i II roku MU Wydziału Biologii, kierunek biotechnologia (pozostałe specjalności) oraz biologia.

Course coordinators

Agnieszka Kwiatek

Learning outcomes

KNOWLEDGE
• Student has acquaintance of current knowledge in key branch of biotechnology, has have knowledge of: virological terminology, the newest research, discoveries and their applications in biotechnology and medicine, and knows the literature of virology (K_W02 Bt1; K_W06 Bt1; K_W09 Bt1; K_W03 Bt2, K_W12 Bt2);
• Student knows the structural, genetic, metabolic and functional diversity of viruses, including viruses pathogenic to humans (K_W02 Bt2; K_W03 Bl2);
• Student knows a different of laboratory methods and techniques, measurement, imaging and research tools used in the virological research and adequately plans to use them to solve given tasks (K_W04 Bt1; K_W05 Bt1; K_W09 Bt1; K_W16 Bl2; K_W16 Bl2);
• Student understands the rules and the molecular mechanisms of replication, multiplication, function and pathogenesis caused by viruses pathogenic to humans (K_W02 Bt2; K_W05 Bl2);
• Student masters his/her knowledge in selected areas of biotechnology for human pathogenic viruses, medical biotechnology and cell and tissue engineering (K_W02 Bt2);
• Student understands the relationships virus - the human organism, using the hypotheses concerning the temporal and spatial determinants of biodiversity (K_W06 Bt2; K_W04 Bl2);
SKILLS
• Student demonstrates abilities of critical analysis, selection of information in virology field, can conclude and formulate own opinion based on data from various sources, especially from electronic sources and media ( K_U03 Bt1; K_U06 Bt1; K_U03 Bt2; K_U07 Bt2; K_U04 Bl2);
• Student analyzes the market for biotechnology products, including products of medical virology (e.g. vaccines and antiviral drugs, kits for virological diagnostics) (K_U16 Bt2);
• Student can suggest ways to carry out specialist measurements and to assess the usefulness of the methods (e.g. virological diagnostics) and can indicate the limits of these methods (K_U16 Bt2; K_U12 Bt2; K_U01 Bl2);
• Student can estimate the environmental risk associated with the applied technology (e.g. preparation of vaccines and antiviral drugs) and effectively counteract these dangers (K_U11 Bt2; K_U12 Bt2; K_U15 Bt2);
SOCIAL AWARNESS
• Student understand the need and can pass information about new biotechnological achievements, including information in the field of molecular virology, general and medical virology and can explain their importance and legitimacy of carry out of basic sciences in this field of knowledge and is able to provide this information in an understandable manner (K_K04 Bt2; K_K01 Bt2; K_K06 Bt1; K_K01 Bl2; K_K03 Bl2);
• Student realizes and understands the need of constantly improve professional and social competence, including permanent additional qualifications and actively update his/her knowledge using the scientific and popular sources involving information about virology and biotechnology with its practical application (K_K04 Bt2; K_K07 Bl2);
• Students demonstrates responsibility for assessing the risks of research techniques in the field of medical virology, and create ergonomic and safe working conditions (K_K03 Bt2; K_K03 Bt1; K_K08 Bl2);
• Student understands the need to fulfill the role of education in society, in the field of the activities based on the knowledge and skills involving information concerned molecular and medical virology (K_K04 Bt2; K_K02 Bl2; K_K03 Bl2);
• Students knows the rules of research ethics and resolves the dilemmas connected to research and science (K_K03 Bt2; K_K05 Bt1; K_K06 Bl2);
• Student uses objective sources of scientific information and carefully concludes resolving practical problems (K_K04 Bt2; K_K11 Bl2);

Assessment criteria

Written exam. The exam includes six or seven open questions.

Practical placement

Unrequired

Bibliography

Books:
1. Piekarowicz A. (2004) Podstawy Wirusologii Molekularnej PWN
2. Webster RG, Granoff A. (1994) Encyclopedia of Virology. Academic Press, Harcourt Brace & Company, Publishers
3. Wagner EK, Hewlett MJ. (2004) Basic Virology. Blackwell Publishing
4. Zaremba L, Borowski J. (2001) Mikrobiologia lekarska, wydanie III, Wydawnictwo Lekarskie PZWL, Warszawa

Web sites:
1. http://ictvdb.bio-mirror.cn/Ictv/ICTVindex.htm
2. http://ictvdb.bio-mirror.cn/Images/Murphy/herpes.htm

Additional information

Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system:

Description of 1400-227WL in USOSweb