Medical aspects of metabolism regulation 1400-227MARM
The aim of the lecture is to:
- answer the question about the causes of metabolic disturbances in the course of metabolic diseases
- describe symptoms, ethiology and diagnosis of some inherited metabolic disorders
- present methods in the identification of the drugs and toxins points of action in metabolic pathways.
- present methods in drug metabolism study
- describe tumor metabolism
- elucidate mechanisms of hormone-induced signal transduction, in normal and pathological condition.
- elucidate mechanisms of the control of food intake.
- describe organs specjalization of metabolic processes.
- presents analitycal methods in medical diagnostics and analyze medical tests results.
Classes are:
- performed as individual laboratory work,
- tightly correlated with the topics presented during the lecture,
- dedicated to extention and the practical application of the knowledge the students gain during the lecture.
Classes are dedicated to indywidual learning of discovery of control points of metabolic pathways and transport processes in normal and pathological condition.
Type of course
Requirements
Prerequisites
Prerequisites (description)
Course coordinators
Learning outcomes
Having completed the course, the student can:
1. presents relationship among the metabolic pathways of various organs and mention exaples of inherited and aquired metabolics disorders
- presents the methods of the identification of the regulatory stages of a metabolic pathway,
- classifies hormones, including steroid and peptide ones,
- explains the significance of hormones in metabolic pathways regulation,
- defines the term “cascade systems”,
- explains the scheme of the mechanism of both steroid and peptide hormones action,
- presents intracellular localization of the basic metabolic processes,
- explains the mechanisms of vital metabolites transport through cellular and subcellular membranes
- plan and execute simple metabolic regulation experiment and draw proper conclusion from the results.
Assessment criteria
Final written exam. Passing the classes is required before taking the exam.
Bibliography
Berg JM, Tymoczko JL, Stryer L (2005) Biochemia, wydanie piąte, PWN, Warszawa
Garrett RH, Grisham CM (2010) Biochemistry, Fourth Editio, Brookes/Cole, Cengage Learning, Boston, MA, USA
Nowak Z, Zawilska JB (red.) (2004) Receptory i mechanizmy przekazywania sygnału. PWN, Warszawa
Gomperts BD, Kramer IM, Tacham PER (2009) Signal Transduction, Second Edition, Academic Press, Burlington, MA, USA
Devlin Th (ed.) (2006) Textbook of Biochemistry with clinical correlations, wydanie siódme, John Wiley&Sons, Inc., Hoboken, NJ, USA
Notes
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Term 2023Z:
None |
Term 2024Z:
None |
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: