Basic genetics 1400-114PGEN
Classes:
I. Cell biology
1. Meiosis during spermatogenesis and oogenesis
2. Mitosis
II. Genetics
1. Basics of classical genetics
2. DNA as genetic material; Mutations;
3. Genetic code
4. Structure and expression of prokaryotic and eukaryotic genes
5. Selected issues of human genetics
III. Molecular methods in environmental research
1. DNA isolation
2. DNA electrophoresis; Polymerase chain reaction (PCR);
3. Sanger sequencing
4. Population genetics (computer analysis)
5. Computer analysis of nucleotide sequences, part 1
6. Computer analysis of nucleotide sequences, part 2
7. Biological molecules databases
Lectures:
I. Cell biology
1. The origin of cell, comparison of a prokaryotic and eukaryotic cells
2. Nucleus
3. The cell cycle
4. Meiosis, gametes and germ cells
II. Basic genetics
1. Organization of pro- and eukaryotic genomes; Structure of genes; Operons;
2. Expression of genetic information in pro- and eukaryotes
3. Regulation of gene expression in pro- and eukaryotes
4. Human genetics
III. Genomes
1. Evolution at the molecular level
2. Genomes of viruses
3. Genomes of bacteria and archeons
4. Nuclear genomes
5. Mitochondrial genomes
6. Plastid genomes
7. Mobile genetic elements
Type of course
Mode
Course coordinators
Learning outcomes
Knowledge (knows, understands):
- knows the structure of prokaryotic and eukaryotic cells (K_W01);
- knows the structure of the cell nucleus (K_W01);
- knows and understands the chromatin organization and molecular mechanisms responsible for its functioning (K_W01);
- understands the molecular mechanisms regulating the cell cycle (K_W01);
- understands the difference between mitotic and meiotic division (K_W01);
- understands importance of mitosis and meiosis (K_W01);
- knows the basics of genetics and molecular biology (K_W01);
- knows the basic terminology used in genetics and molecular biology (K_W02, K_W06);
- knows the mechanisms of evolution at the molecular level (K_W01);
- knows the methods of molecular biology used in environmental research (K_W01, K_W06).
Skills (can):
- can recognize and explain the phenomena related to the organization and expression of genetic information (K_U04, K_U09);
- can independently study the recommended literature and use the Internet resources (K_U05, K_U013);
- can choose molecular biology methods that allow for the identification of an organism and estimation of genetic variation (K_U02, K_U010);
- can use the tools for searching databases of nucleotide and amino acid sequences (K_U05).
Social competences (is ready to):
- is ready to expand own knowledge and popularize the importance of molecular biology methods in environmental research and in environmental protection (K_K02).
Assessment criteria
Classes - evaluation criteria: student should not have been absent more than twice. The final mark will be based on the sum of points in the written test.
The course will be evaluated based on a written examination (positive evaluation of exercises is needed before the exam).
Practical placement
None
Bibliography
Literatura
Ekologia molekularna. Joanna R. Freeland. PWN 2008.
Genomy. T. A. Brown. PWN 2012
Genetyka. Ilustrowany przewodnik. Eberhard Passarge Wydawnictwo Lekarskie PZWL. 2004
Genetyka człowieka. Rozwiązywanie problemów medycznych. B.R. Korf, 2003.
Podstawy biologii komórki. B. Alberts i wsp., PWN, Warszawa 1999
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: