Biothermodynamics 1200-2SPEC82M
Laws of thermodynamics (entropy and its statistical interpretation, typical errors in interpretation, so-called, thermodynamic paradoxes related to the 2nd Law of Thermodynamics).
Helmholtz potential, Gibbs potential, chemical potential (transport phenomena – diffusion, diffusion through (semi-permeable) membrane /membrane, osmosis)
Thermodynamical description of (bio)chemical reactions (“direction” of reaction, chemical equilibrium, peculiar character of biochemical reactions, typical interpretative errors, Marcus theory in biochemical systems).
Open biochemical systems (laws of thermodynamics in biological systems, interpretation of entropy in aspect of working).
Bioenergetics.
Non-equilibrium systems (stationary state, conjugated processes, dissipation of energy, Prigogine’s rule of minimum entropy production).
Fluctuations and dissipative structures, biological oscillations, selforganizing and evolution, thermodynamic aspects of biological evolution).
Elements of information theory. Elements of theory of deterministic chaos. Use of chaos theory together with thermodynamics of nonequilibrium processes for attempt of explanation of ontogenesis of some diseases (e.g. cancer, Alzheimer or Parkinson disease).
Examples of thermodynamic modeling (simulation) of biochemical systems (from biotechnology)(e.g. systems with enzymatic catalysis).
Total workload: 75 hours
including:
- class participation - 30 hours
- consultations with the instructor - 20 hours
- exam preparation - 25 hours
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Term 2025L:
Laws of thermodynamics (entropy and its statistical interpretation, typical errors in interpretation, so-called, thermodynamic paradoxes related to the 2nd Law of Thermodynamics). Helmholtz potential, Gibbs potential, chemical potential (transport phenomena – diffusion, diffusion through (semi-permeable) membrane /membrane, osmosis) Thermodynamical description of (bio)chemical reactions (“direction” of reaction, chemical equilibrium, peculiar character of biochemical reactions, typical interpretative errors, Marcus theory in biochemical systems). Open biochemical systems (laws of thermodynamics in biological systems, interpretation of entropy in aspect of working). Bioenergetics. Non-equilibrium systems (stationary state, conjugated processes, dissipation of energy, Prigogine’s rule of minimum entropy production). Fluctuations and dissipative structures, biological oscillations, selforganizing and evolution, thermodynamic aspects of biological evolution). Elements of information theory. Elements of theory of deterministic chaos. Use of chaos theory together with thermodynamics of nonequilibrium processes for attempt of explanation of ontogenesis of some diseases (e.g. cancer, Alzheimer or Parkinson disease). Examples of thermodynamic modeling (simulation) of biochemical systems (from biotechnology)(e.g. systems with enzymatic catalysis). |
Prerequisites (description)
Course coordinators
Main fields of studies for MISMaP
General: chemistry physics biology biotechnology | Term 2025L: biology biotechnology physics chemistry |
Type of course
General: elective courses | Term 2025L: optional courses |
Mode
General: Remote learning Classroom | Term 2025L: Classroom Remote learning |
Learning outcomes
Intentionally, there can be different starting points, and therefore this can be introductory to medium course. This depends on previous knowledge on this matter. Student solves simple problems concerning matter-energy balance in closed and open (particularly of biological interest) systems using thermodynamic tools. Is capable to follow more sophisticated considerations on this subject in scientific literature.Intentionally, there can be different starting points, and therefore this can be introductory to medium course. This depends on previous knowledge on this matter.
After the lecture: the student understands the basic concepts of thermodynamics and their application to biological systems. Solves simple problems involving material and energy balance in closed and open systems (with particular emphasis on biological problems) using thermodynamic tools. Is able to follow with understanding more advanced discussions in this area in the scientific literature. Is prepared to further independently deepen their knowledge in the chosen field. Student solves simple problems concerning matter-energy balance in closed and open (particularly of biological interest) systems using thermodynamic tools. Is capable to follow more sophisticated considerations on this subject in scientific literature.
Assessment criteria
Maksymalna liczba nieobecności nie powinna przekroczyć 20% czasu zajęć, czyli 6 godzin.
Podstawą zaliczenia jest aktywność studenta oraz (krótki) pisemny test z oceną.
Practical placement
not concern
Bibliography
Established in consultation with teacher (in accordance with needs)
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: