Chemistry of Heterocyclic Compounds 1200-2SPEC122M
This lecture covers the following topics:
- Three-membered rings with oxygen, nitrogen and sulphur; biological activity (pheromones, anti-cancer drugs), synthesis and reactivity;
- Four-membered rings; synthesis and reactivity; beta-lactam antibiotics
- Fife-membered rings (furans, pyroles, thiophenes); synthesis; utilization in drug synthesis;
- Six-membered rings (pyridines, pyranes); synthesis and reactivity (electrophilic and nucleophilic substitution); utilization in alkaloid synthesis;
- Quinolines, isoquinolines, indoles; occurrence in the nature; utilization in synthesis of dyestuffs and drugs;
- Application of heterocyclic compounds in organic synthesis;
- Heterocyclic compounds in new technologies;
Type of course
Requirements
Prerequisites (description)
Course coordinators
Mode
Learning outcomes
Students will acquire knowledge encompassing synthesis, reactivity and biological activity of chosen heterocyclic compounds.
Practical placement
none
Bibliography
1. Heterocyclic Chemistry, John A. Joule, Keith Mills, A John Wiley & Sons, Ltd.,
Publication;
2. I. Młochowski, Chemia związków heterocyklicznych, PWN
3. T. Eichler, S. Hauptmann, Wiley-VCH, Weinheim, The Chemistry of
Heterocycles;
4. Julio Alvarez-Builla, Juan Jose Vaquero, and José Barluenga, Modern
Heterocyclic Chemistry Volume 4;
5. John A. Joule, Keith Mills, Heterocyclic Chemistry at a Glance, Blackwell
Publishing;
6. Stephen Po Stanforth, Natural Product Chemistry at a Glance, Blackwell
Publishing;
Notes
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Term 2023L:
None |
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: