Chemistry of Heterocyclic Compounds 1200-2SPEC122M
This lecture covers the following topics:
- Three-membered rings with oxygen, nitrogen and sulphur; biological activity (pheromones, anti-cancer drugs), synthesis and reactivity;
- Four-membered rings; synthesis and reactivity; beta-lactam antibiotics
- Fife-membered rings (furans, pyroles, thiophenes); synthesis; utilization in drug synthesis;
- Six-membered rings (pyridines, pyranes); synthesis and reactivity (electrophilic and nucleophilic substitution); utilization in alkaloid synthesis;
- Quinolines, isoquinolines, indoles; occurrence in the nature; utilization in synthesis of dyestuffs and drugs;
- Application of heterocyclic compounds in organic synthesis;
- Heterocyclic compounds in new technologies;
Type of course
Requirements
Prerequisites (description)
Course coordinators
Mode
General: Classroom | Term 2024L: Blended learning | Term 2025L: Classroom |
Learning outcomes
Students will acquire knowledge encompassing synthesis, reactivity and biological activity of chosen heterocyclic compounds.
Practical placement
none
Bibliography
1. Heterocyclic Chemistry, John A. Joule, Keith Mills, A John Wiley & Sons, Ltd.,
Publication;
2. I. Młochowski, Chemia związków heterocyklicznych, PWN
3. T. Eichler, S. Hauptmann, Wiley-VCH, Weinheim, The Chemistry of
Heterocycles;
4. Julio Alvarez-Builla, Juan Jose Vaquero, and José Barluenga, Modern
Heterocyclic Chemistry Volume 4;
5. John A. Joule, Keith Mills, Heterocyclic Chemistry at a Glance, Blackwell
Publishing;
6. Stephen Po Stanforth, Natural Product Chemistry at a Glance, Blackwell
Publishing;
Notes
|
Term 2024L:
None |
Term 2025L:
None |
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: