Application of Enzymes in Organic Synthesis 1200-2MON7Z
The lecture covers the following topics:
- general information concerning of enzymes,
- classification of enzymes,
- enzyme kinetics,
- pros and cons of biocatalysis,
- organic synthesis catalysed by oxyreductases, lyases, isomerases, hydrolases, transferases and ligases,
- biocatalysis in organic solvents.
Type of course
Mode
Prerequisites (description)
Course coordinators
Learning outcomes
The student of chemistry knows and understands:
K_W02 - knows the basics of biochemistry and understands the importance of chemical phenomena in processes occurring in living nature,
K_W05 - has in-depth knowledge and skills in the selected chemical specialization allowing the use of methods and concepts appropriate for this specialization and allowing for independent research work,
K_W10 - has a good orientation in the current directions of development of chemistry and the latest scientific discoveries in a given chemical specialization.
The student of chemistry is able to:
K_U08 - has advanced knowledge and skills allowing the use of specialist literature, databases and other sources of information, as well as the ability to assess the reliability of the information obtained,
K_U09 - is able to apply the acquired knowledge to related scientific disciplines, as well as work in interdisciplinary teams,
K_U11 - is able to discuss the place of chemistry in the system of exact and natural sciences, and its importance for the development of our civilization,
K_U12 - is able to present the results of the most important discoveries made in the field of chemistry and related sciences in a way that is understandable also to non-specialists,
K_U13 - Is able to independently acquire knowledge and develop their professional skills using various sources (written and electronic), including foreign ones.
The student of chemistry is ready to:
K_K01 - understands the need and knows the possibilities of continuous education, is able to independently search for information in literature (including foreign languages) and use the advice of experts,
K_K06 - is able to think and act in a creative and enterprising way.
The student of medical chemistry knows and understands:
K_W04 - modern methods of synthesis of complex organic compounds, including those with therapeutic effects, using classical and the latest achievements in organic synthesis,
K_W16 - selected, advanced chemical, physical and biological phenomena and processes.
The student of medical chemistry is able to:
K_U12 - independently acquire knowledge and develop their professional skills, using various sources, including those in a foreign language,
K_U20 - use professional literature, databases and other sources of information, and the ability to assess the reliability of the information obtained.
The student of medical chemistry is ready to:
K_K01 - continuously educate themselves and independently search for information in the literature, including foreign languages,
After the completion of the course the following tasks should accomplished:
- enzymes as catalysts,
- kinetics of enzymatic reactions,
- classicication of enzymes,
- general knowledge of enzymatic methods for synthesis organic compounds.
Assessment criteria
Credit for a grade (test with closed questions).
0% - 50% 2
51% - 60% 3
61% - 70% 3,5
71% - 80% 4
81% - 90% 4,5
91% -100% 5
Attendance is mandatory. Maximum number of absences required to achieve the learning outcomes: 1.
Practical placement
Does not concern.
Bibliography
1.Lubert Stryer, Biochemistry, W.H. Freeman and Company, New York and Basingstoke, 1995
2.Robert K. Murray, Daryl K. Granner, Peter A. Mayes, Victor W. Rodwell, Harpers Biochemistry, The McGraw-Hill Companies, Inc., New York, 2000
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: