Natural Compounds and Their Impact on Drug Design 1200-2MON5L
The lecture topics are the following: a review on main groups of secondary metabolites with distinguished biological activity (glycosides, alkaloids, steroids, terpenes, antibiotics): the most important plant raw materials; modern methods of increasing of selected metabolites content in plant material; alkaloids with strong activity toward nervous system as lead compounds in the search for counterpain drugs; natural substances exhibiting antineoplastic, mutagenic and carcinogenic activity and their influence on advances of chemotherapy; natural anticancer drugs of plant origin; drug acting on the nervous system and their non-medical application.
Estimated student workload per semester: 37.5 hours, including:
• 15 hours of class participation
• 7.5 hours of consultations
• 15 hours of exam preparation
Main fields of studies for MISMaP
biotechnology
chemistry
Type of course
elective courses
Prerequisites (description)
Course coordinators
Mode
Learning outcomes
KNOWLEDGE: After completing the course, the student knows and understands
K_W01, K_W05, K_W08, K_W10
• has extensive knowledge of the place of chemistry in the system of exact and natural sciences and its importance for the development of humanity;
• has in-depth knowledge and skills in the selected chemical specialization, allowing them to use the methods and concepts appropriate for this specialization and enabling independent research;
• has advanced knowledge and skills in computational methods appropriate for a given chemical specialization;
• has a good understanding of current trends in chemistry and the latest scientific discoveries in a given chemical specialization;
• in particular:
• knows and understands the general principles governing the search for and synthesis of new medicinal substances;
SKILLS: After completing the course, the student is able to
K_U08, K_U11
• possess advanced knowledge and skills enabling the use of professional literature, databases, and other sources of information, and to assess the reliability of the information obtained;
• be able to discuss the place of chemistry in the system of exact and natural sciences and its importance for the development of our civilization;
• explain, using selected examples, the importance of natural compounds in drug synthesis.
SOCIAL COMPETENCES: After completing the course, the student is ready for
K_K01
• continuous learning and independent search for information in literature, including foreign languages.
Assessment criteria
Written exam (in-class or remotely) or semester paper (presentation on a topic agreed upon with the lecturer). Attendance is mandatory, with two absences permitted.
Bibliography
1. Zejc Alfred, Gorczyca Maria "Chemia leków", Wydawnictwo Lekarskie PZWL, 2009
2. Silverman Richard "Chemia organiczna w projektowaniu leków", WNT, 2004
3. Patrick G."Chemia leków. Krótkie wykłady.", PWN, 2009
4. A. Kołodziejczyk „Naturalne związki organiczne", PWN, Warszawa 2006
5. E. J. Corey, Barbara Czakó, László Kürti "Molecules and Medicine", J. Wiley & Sons, 2007
Notes
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Term 2024L:
None |
Term 2025L:
None |
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: