Natural Compounds and Their Impact on Drug Design 1200-2MON5L
The lecture topics are the following: a review on main groups of secondary metabolites with distinguished biological activity (glycosides, alkaloids, steroids, terpenes, antibiotics): the most important plant raw materials; modern methods of increasing of selected metabolites content in plant material; alkaloids with strong activity toward nervous system as lead compounds in the search for counterpain drugs; natural substances exhibiting antineoplastic, mutagenic and carcinogenic activity and their influence on advances of chemotherapy; natural anticancer drugs of plant origin; drug acting on the nervous system and their non-medical application.
Main fields of studies for MISMaP
biotechnology
chemistry
Type of course
elective courses
Prerequisites (description)
Course coordinators
Mode
Learning outcomes
After completing the lecture, a student should be able to explain the significance of natural compounds for the drug’s synthesis and give examples. Student should be able to understand major rules for seeking and synthesis of new drugs.
Assessment criteria
The comprehensive written exam.
Bibliography
1. Zejc Alfred, Gorczyca Maria "Chemia leków", Wydawnictwo Lekarskie PZWL, 2009
2. Silverman Richard "Chemia organiczna w projektowaniu leków", WNT, 2004
3. Patrick G."Chemia leków. Krótkie wykłady.", PWN, 2009
4. A. Kołodziejczyk „Naturalne związki organiczne", PWN, Warszawa 2006
5. E. J. Corey, Barbara Czakó, László Kürti "Molecules and Medicine", J. Wiley & Sons, 2007
Notes
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Term 2023L:
None |
Additional information
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