Natural Compounds and Their Impact on Drug Synthesis 1200-2EN-MON1L
The lecture topics are the following: a review on main groups of secondary metabolites with distinguished biological activity (glycosides, alkaloids, steroids, terpenes, antibiotics): the most important plant raw materials; modern methods of increasing of selected metabolites content in plant material; alkaloids with strong activity toward nervous system as lead compounds in the search for counterpain drugs; natural substances exhibiting antineoplastic, mutagenic and carcinogenic activity and their influence on advances of chemotherapy; natural anticancer drugs of plant origin; drug acting on the nervous system and their non-medical application.
Estimated student workload per semester: 37.5 hours, including:
• 15 hours of class participation
• 7.5 hours of consultations
• 15 hours of exam preparation
Main fields of studies for MISMaP
chemistry
biotechnology
Course coordinators
Type of course
elective courses
Mode
General: Classroom | Term 2024L: Blended learning Classroom |
Prerequisites (description)
Learning outcomes
KNOWLEDGE: After completing the course, the student knows and understands
K_W01, K_W05, K_W08, K_W10
• has extensive knowledge of the place of chemistry in the system of exact and natural sciences and its importance for the development of humanity;
• has in-depth knowledge and skills in the selected chemical specialization, allowing them to use the methods and concepts appropriate for this specialization and enabling independent research;
• has advanced knowledge and skills in computational methods appropriate for a given chemical specialization;
• has a good understanding of current trends in chemistry and the latest scientific discoveries in a given chemical specialization;
• in particular:
• knows and understands the general principles governing the search for and synthesis of new medicinal substances;
SKILLS: After completing the course, the student is able to
K_U08, K_U11
• possess advanced knowledge and skills enabling the use of professional literature, databases, and other sources of information, and to assess the reliability of the information obtained;
• be able to discuss the place of chemistry in the system of exact and natural sciences and its importance for the development of our civilization;
• explain, using selected examples, the importance of natural compounds in drug synthesis.
SOCIAL COMPETENCES: After completing the course, the student is ready for
K_K01
• continuous learning and independent search for information in literature, including foreign languages.
Assessment criteria
Final and retake exam in writing or credit work agreed with the lecturer.
Practical placement
N/A
Bibliography
1. Zejc Alfred, Gorczyca Maria "Chemia leków", Wydawnictwo Lekarskie PZWL, 2009
2. Silverman Richard "Chemia organiczna w projektowaniu leków", WNT, 2004
3. Patrick G."Chemia leków. Krótkie wykłady.", PWN, 2009
4. A. Kołodziejczyk „Naturalne związki organiczne", PWN, Warszawa 2006