Organic Chemistry - Methods of Identification - laboratory 1200-1ZMCHOMIL4
The laboratory covers the basics of synthesis and analysis of organic compounds. Students work individually.
During the course students learn basic laboratory techniques (crystallization, extraction, distillation, distillation under reduced pressure) and basic apparatus used in the laboratory of organic chemistry.
By conducting the synthesis of simple organic compounds, students practically apply and consolidate their knowledge of organic chemistry, learn proper organization of their work in accordance with safety requirements, learn to observe and control the course of the experiment and keep the laboratory notes l in accordance with accepted standards.
Moreover, students learn and practically apply basic techniques of the analysis, identification and determiation of the structure of organic compounds. The above are: classical methods of chemical analysis, spectroscopic methods, in particular nuclear magnetic resonance (NMR) and UV-Vis spectroscopy and basic chromatography techniques - thin layer chromatography (TLC) and preparative column chromatography.
Particular procedures of synthesis and instructions for exercise are provided, in advance, by the instructors.
Two excused absences are allowed, although all exercises must be completed.
Type of course
Mode
Requirements
Prerequisites (description)
Course coordinators
Learning outcomes
Upon completing the laboratory student:
- knows the rules of the safe work in the organic chemistry laboratory and can find information regarding the hazards related to the particular chemicals
- can uderstand the given simple synthetic procedure and, on according to it, can perform required laboratory operations (set up the galssware, conduct the recation, isolate and purify the product),
- is able to propose a rational method of separation of mixture of compounds and purification of its components. Can practically berform the above conducting simple destillation, liquid/liquid extraction, crystallization, purification using column chroatography,
- can choose a proper eluent and then perform a thin layer chromatography (TLC),
- knows the basics of interpretation of nuclear magnetic resonance (NMR) spectra,
- can propose an appropriate spectroscopic technique, in particular UV-Vis, NMR, to identify the structure and determine the purity of organic compounds,
- knows the basic methods of classical chemical identification of organic compunds ,
- can observe the course of the experiment and keep the laboratory notes.
Assessment criteria
- Requirements for passing the course:
1) Completion of all individual syntheses and identification tasks and approval of written reports of each individual synthesis
2) Passing the OHS test (OHS, laboratory techniques, calculations), the test can be retaken. Without passing this test student is not allowed do start the practical exercises.
3) Passing all the partial test. Each test consists of two parts - theoretical (8 points) and concerning the performance of a given exercise (2 points). It is required to obtain at least 50% from all partial tests and at least 50% from the theoretical part of each test (4 points). The theoretical parts of each test can be corrected during the semester during classes. Students decide when they want to retake tests. The part of the test concerning the performance of a given exercise cannot be corrected.
- The final grade consists of:
1) grades obtained from tests,
2) grades obtained from exercises,
3) assessment of the overall quality of work, in particular compliance with the requirements of occupational health and safety.
- Conditions for passing in the correction session:
Students who did not complete all practical exercises within the deadline may do ONE exercise during the correction session. Failure to perform more than one exercise makes it impossible to pass a course.
Students who did not meet the credit criteria due to tests criteria can improve any number of tests in a maximum of two appointments.
Schedules for retaking the tests and practical exercises are set individually.
ATTENTION - The above arrangements, especially with regard to assigning additional terms, are subject to change due to the epidemiological situation and related regulations.
Practical placement
not applicable
Bibliography
Basics of organic chemistry:
1. (en) J. E. McMurry, Organic Chemistry (8th ed.), Brooks/Cole Cengage Learning, Belmont 2012 (and other editions).
2. (en) R.T. Morrison, R.N. Boyd, Chemia Organiczna (6th ed.), Prentice-Hall Inc., Engelwood Cliffs 1992 (and other editions).
Practical organic chemistry:
1. (pl) Misicka A., Orłowska A., Piekarska-Bartoszewicz B., Witkowska E., Podstawy preparatyki organicznej. Skrypt dla studentów II roku Wydziału Chemii UW, LIBER, Warszawa 2012 (and other editions).
2. (en) A. Vogel,Textbook of Practical Organic Chemistry (5th ed.), Longman Group UK Ltd., Harlow 1984.
3. (pl) J. Wróbel, Preparatyka i elementy syntezy organicznej, PWN, Warszawa 1983.
Identyfikacja związków organicznych:
1. (pl) K. Bańkowski, A. Krawczyk, R. Siciński, J. Stępiński, A. Temeriusz, Ćwiczenia z organicznej analizy jakościowej i chemii bioorganicznej, Wyd. UW, Warszawa 1990.
A. (pl) Berthillier, Chromatografia i jej zastosowanie, PWN, Warszawa 1975.
3. (pl) Opieńska-Blauth, H. Kraczkowski, H. Brzuszkiewicz, Zarys
chromatografii cienkowarstwowej, PWRiL, Warszawa 1976.
4. (pl) M. Szafran, Z. Dega-Szafran, Określanie struktury związków
organicznych metodami spektroskopowymi, PWN, Warszawa 1988.
5. (pl) W. Zieliński, A. Rajca (red.), Metody spektroskopowe i ich
zastosowanie do identyfikacji związków organicznych, WNT, Warszawa 1995.
6. (en) R. M. Silverstein, F.X. Webster, D.J. Kiemle, D. L. Bryce, Spectrometric Identification of Organic Compounds (8th ed.), Wiley, 2015 (and prev. eds.).
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: