Methods of Organic Compounds Identification B - seminar 1200-1MIZOBP6
The goal of the seminar is to gain ability to solve problems about separation of mixtures of organic compounds, determining their purity and identifying them.
Exercises solved during seminar refer to following subjects:
1. Chemical methods of compound identification
1.1 Chemical analysis of organic compound
- solubility groups
- functional group identification
1.2 Separating organic compound mixtures by classical methods
2. Chromatographic methods
- gas chromatography
- liquid (column) chromatography
- thin-layer chromatography
3. Spectroscopic methods
- ultraviolet-visible chromatography (UV-Vis)
- infrared chromatography (IR)
- nuclear magnetic resonance chromatography 1H NMR, 13C NMR
- mass spectrometry (MS)
Estimated student workload per semester – 40 hours, including:
participation in classes: 15 hours
preparation for individual classes: 10 hours
preparation for the final test: 15 hours
Type of course
Mode
Prerequisites (description)
Course coordinators
Learning outcomes
KNOWLEDGE:
After completing the course, the student:
K_W08, K_W09, K_W11, K_W14
1) Possesses advanced knowledge of organic chemistry and biochemistry (nomenclature, structure of organic compounds, chemical reactions, reaction mechanisms, methods of synthesis, occurrence, and applications). Understands the significance of chemical phenomena in processes occurring in living nature.
2) Knows the methods of identification of organic compounds using chemical, chromatographic, and spectroscopic techniques.
3) Possesses advanced theoretical knowledge of various molecular spectroscopies and understands their applications.
4) Has advanced knowledge of the design and operation of modern measuring instruments supporting scientific research in chemistry.
SKILLS:
After completing the course, the student:
K_U08, K_U09, K_U15, K_U16, K_U17
1) is able to analyze problems in the field of organic chemistry, including investigating reaction mechanisms. Can perform syntheses of selected organic compounds. Can separate mixtures of selected organic compounds and purify the obtained components.
2) is able to identify selected organic compounds using chemical, chromatographic, and spectroscopic techniques.
3)is capable of skillfully planning and conducting basic research and experiments in chemistry, and possesses the ability to observe, critically evaluate own results, and discuss measurement errors.
4) can apply appropriate methods, techniques, and research tools within a given chemical specialization necessary to solve a stated problem, including advanced information and communication technologies.
5) is able to carry out measurements of selected physicochemical quantities, determine their values, and assess the reliability of the obtained results. Can operate selected measuring instruments.
Assessment criteria
Mandatory attendance at all classes. Only 1 absence is allowed.
Absence during the final test must be excused with a sick leave.
Final test (open questions and problems to solve) - 100%
In addition, at the beginning of each class, a short (10-minute) quiz is held, for which students can earn extra points.
Practical placement
not applicable
Bibliography
1. O. Demchuk, M. Topyła, K. Kapłon, „Ćwiczenia laboratoryjne z identyfikacji związków organicznych”, Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej, 2014.
2. K. Bańkowski, A. Krawczyk, R. Siciński, J. Stępiński, A. Temeriusz – Ćwiczenia z organicznej analizy jakościowej i chemii bioorganicznej - Wyd. UW, 1990.
3. A. Vogel - Preparatyka organiczna - WNT, 1984
4. R. Walczyna, J. Sokołowski, G. Kupryszewski - Analiza związków organicznych - Wyd. Uniw. Gdańskiego, 1996.
5. Z. Witkiewicz, Podstawy chromatografii i technik elektromigracyjnych, PWN, 2017
6. A. Berthillier - Chromatografia i jej zastosowanie - PWN, 1975.
7. Z. Witkiewicz – Podstawy chromatografii - WNT, 2000.
8. M. Szafran, Z. Dega-Szafran - Określanie struktury związków organicznych metodami spektroskopowymi - PWN, 1988.
9. R. M. Silverstein, F.X. Webster, D.J. Kiemle Spektroskopowe metody identyfikacji związków organicznych - PWN 2007.
10.F. Wehrli, T. Wirthlin - Interpretacja widm w spektroskopii 13C NMR - PWN, 1985
11. A. Ejchart, L. Kozerski - Spektroskopia magnetycznego rezonansu jądrowego 13C - PWN, 1981, 1988.
12. W. Zieliński, A. Rajca (red) - Metody spektroskopowe i ich zastosowanie do identyfikacji związków organicznych - WNT, 1995.
13. C.N.R. Rao, – Spektroskopia elektronowa związków organicznych - PWNT, 1982.
14. B.D. Hames, N.M. Hooper, J.D. Houghton - Krótkie wykłady: Biochemia - PWN, 2001.
15. L. Kłyszejko-Stefanowicz - Ćwiczenia z biochemii - PWN, 1999.
16. R.K. Murray, D.K. Granner, P.A. Mayes, V.W. Rodwell - Biochemia Harpera - PZWL, 2004.
17. a) R.T. Morrison, R.N. Boyd - Chemia Organiczna - PWN, 1998. b) J. McMurry - Chemia Organiczna - PWN, 2005.
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: