Basic Biochemistry 1200-1ELBIOCHW4
Introduction: bonds in biomolecules, macromolecules, cell structure. Structure of biological membranes. Transport across membranes. Properties of amino acids. Peptide bonds. Primary, secondary, tertiary, and quaternary structure of proteins. Relationship between protein structure and function. Catalysis and free energy. Structure of enzymes, their function, classification, and action.
Carbohydrates (classification, functions, the most important mono-, di-, and polysaccharides and their structure and role). Biological oxidation. Basic stages of cellular respiration and their characteristics (glycolysis, bridging reaction, Krebs cycle, respiratory chain). Substrate and oxidative phosphorylation.
Nucleic acids: DNA, mRNA, rRNA, tRNA – structure and spatial structure. DNA replication and transcription. The genetic code. Protein biosynthesis (translation).
Total student workload: 40 hours, including:
lecture attendance – 15 hours
independent study after each lecture – 7 hours
consultations with the lecturer – 8 hours
exam preparation – 10 hours
Main fields of studies for MISMaP
Course coordinators
Type of course
Mode
Requirements
Prerequisites (description)
Learning outcomes
After completing the lecture, the student:
- knows the basic principles and conditions (“molecular logic of life”) governing the organization and interactions of organic compounds present in organisms,
- understands and can explain the fundamentals of phenomena and processes occurring in the body (including the transport of compounds, gene replication and expression, energy acquisition, and its storage in ATP),
- can apply and use their existing knowledge, including in organic chemistry, to analyze selected processes and reactions occurring in the body.
K_W01: The student knows and understands the role and place of chemistry in the structure of the exact and natural sciences and its contribution to the development of our civilization. They know basic chemical concepts and laws, are familiar with chemical symbols, nomenclature, and notation, and understand the notation of chemical reactions.
K_W08: The student has an advanced knowledge and understanding of organic chemistry and biochemistry (nomenclature, structure of organic compounds, chemical reactions, reaction mechanisms, methods of preparation, occurrence, and applications). They understand the importance of chemical phenomena in processes occurring in living nature.
K_U08: The student can analyze problems in organic chemistry, including investigating the mechanisms of organic reactions. They can synthesize selected organic compounds. They can separate mixtures of selected organic compounds and purify the obtained components.
Assessment criteria
Lectures are obligatory. Acceptable limit of absence - 2 lectures.
Final written exam, at least 60% of points are needed to pass.
Bibliography
J.M. Berg, J.L. Tymoczko, L. Stryer Biochemia krótki kurs PWN 2013
B. Alberts, D. Bray, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter, Podstawy biologii komórki.H.R. Matthews, R.A. Freedland, R.L. Miesfeld, Biochemia i biologia molekularna w zarysie
Additional information
Information on level of this course, year of study and semester when the course unit is delivered, types and amount of class hours - can be found in course structure diagrams of apropriate study programmes. This course is related to the following study programmes: