Nanomaterials in Medical Chemistry 1200-1CHMNANW6
Historical perspective and introduction to nanomaterials. Importance of nanoscale, definition and classification of nanomaterials in terms of size, shape and composite material. Analytical methods (quantitative and qualitative), physicochemical and structural techniques used in the study of nanostructures. Lipid nanoparticles: Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLC). Polymer nanoparticles, nanogels and dendrimers. Methods of lipid, polymer and dendrimeric nanomaterials synthesis. The importance of microfluidic techniques in nanostructure technology and tissue engineering. Porous and mesoporous silica nanomaterials. Metallic nanoparticles, methods of production, modification and functionalization. Magnetic and superparamagnetic nanoparticles. Carbon nanomaterials. Application of nanomaterials as drug carriers. Nanomaterials in regenerative medicine. Nanosensors in medical diagnostics. Nanomaterials in medical imaging.
Course coordinators
Type of course
Learning outcomes
The student knows and understands:
• K_W06 – fundamentals of physical chemistry in the field of interfacial processes and mass transport, essential for describing the functioning of nanostructures;
• K_W07 – concepts of inorganic and bioinorganic chemistry in relation to metallic and silica nanomaterials;
• K_W09 – chemical components of living organisms and their interactions with nanomaterials;
• K_W17 – aspects of the structure and action of drugs and drug delivery systems using nanomaterials.
The student is able to:
• K_U06 – plan and perform basic experiments on interfacial phenomena and mass transport processes;
• K_U10 – identify bioorganic compounds and evaluate their interactions with nanostructures;
• K_U15 – plan and analyze nanomaterial studies, assessing measurement errors;
• K_U16 – use measurement equipment to determine the physicochemical properties of nanostructures. Is ready to:
• K_K01 – critically evaluate knowledge regarding nanomaterials and their safety;
• K_K05 – understand the impact of nanotechnology on the environment and health;
• K_K07 – continually expand knowledge in the field of medicinal chemistry and nanoscience.
Assessment criteria
A multiple-choice exam (30 questions). Passing the course requires familiarity with the topics covered in the lectures and the primary literature.
Absences allowed: 2 classes (20%).
Passing criterion: ≥ 60% of the exam points.
Student workload:
Class participation: 30 hours
Preparation for classes and the exam: 30 hours
Literature reading and consultations: 10 hours
Note preparation and examples: 10 hours
Total: 80 hours
Practical placement
N/A
Bibliography
1. Principles of Nanomedicine. Bhattacharjee S. Jenny Stanford Publishing, 2019 Singapore.
2. Handbook of nanotechnology. Bharat B. (Ed). Springer-Verlag 2010, Berlin.
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Term 2024L:
1. Principles of Nanomedicine. Bhattacharjee S. Jenny Stanford Publishing, 2019 Singapore. |
Term 2025L:
1. Principles of Nanomedicine. Bhattacharjee S. Jenny Stanford Publishing, 2019 Singapore. |
Notes
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Term 2024L:
Lecture in the academic year 2024/25 conducted remotely (online), on the Google Meet platform |
Term 2025L:
Lecture in the academic year 2024/25 conducted remotely (online), on the Google Meet platform |
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: